Manufacturer supply high quality 3,5-DIBENZYLOXYBENZOIC ACID 28917-43-3 with GMP standards
- Molecular Formula: C21H18 O4
- Molecular Weight: 334.372
- Vapor Pressure: 0mmHg at 25°C
- Melting Point: 214 °C
- Refractive Index: 1.626
- Boiling Point: 539.1 °C at 760 mmHg
- Flash Point: 193.1 °C
- PSA： 55.76000
- Density: 1.232 g/cm3
- LogP: 4.54280
3,5-DIBENZYLOXYBENZOIC ACID(Cas 28917-43-3) Usage
InChI:InChI=1/C19H14O4/c20-19(21)14-11-17(22-15-7-3-1-4-8-15)13-18(12-14)23-16-9-5-2-6-10-16/h1-13H,(H,20,21)
28917-43-3 Relevant articles
Allosteric Guest Binding in Chiral Zirconium(IV) Double Decker Porphyrin Cages
Bruekers, Jeroen P. J.,Hellinghuizen, Matthijs A.,Vanthuyne, Nicolas,Tinnemans, Paul,Gilissen, Pieter J.,Buma, Wybren Jan,Naubron, Jean-Valère,Crassous, Jeanne,Elemans, Johannes A. A. W.,Nolte, Roeland J. M.
, p. 607 - 617 (2021)
Chiral zirconium(IV) double cage sandwic...
Synthesis of alternating polystyrene/poly(ethyleneoxide) branched polymacromonomers
Deimede, Valadoula,Kallitsis, Joannis K.
, p. 467 - 473 (2002)
Newly designed PS/PEO alternating branch...
Biological Characterization, Mechanistic Investigation and Structure-Activity Relationships of Chemically Stable TLR2 Antagonists
Bermudez, Marcel,Grabowski, Maria,Murgueitio, Manuela S.,Rademann, J?rg,Rudolf, Thomas,Tiemann, Markus,Varga, Péter,Weindl, Günther,Wolber, Gerhard
, (2020/06/08)
Toll-like receptors (TLRs) build the fir...
Synthesis and comparative structure-activity study of carbohydrate-based phenolic compounds as α-glucosidase inhibitors and antioxidants
MacHida, Shota,Mukai, Saki,Kono, Rina,Funato, Megumi,Saito, Hiroaki,Uchiyama, Taketo
, (2019/12/04)
Twenty-one natural and unnatural phenoli...
Synthesis, structure activity relationship and in vitro anti-influenza virus activity of novel polyphenol-pentacyclic triterpene conjugates
Li, Haiwei,Li, Man,Xu, Renyang,Wang, Shouxin,Zhang, Yongmin,Zhang, Lihe,Zhou, Demin,Xiao, Sulong
, p. 560 - 568 (2019/01/03)
It is urgently necessary to develop more...
28917-43-3 Process route
-
-
99-10-5
3,5-Dihydroxybenzoic acid
-
-
100-39-0
benzyl bromide
-
-
28917-43-3
3,5-dibenzyloxybenzoic acid
| Conditions | Yield |
|---|---|
|
3,5-Dihydroxybenzoic acid; benzyl bromide;
With
potassium carbonate;
In
N,N-dimethyl-formamide;
With
sodium hydroxide;
In
methanol;
for 1h;
Reflux;
|
100%
|
|
With
potassium carbonate;
In
N,N-dimethyl-formamide;
|
-
-
50513-72-9
(3,5-di-benzyloxy)benzoic acid benzyl ester
-
-
28917-43-3
3,5-dibenzyloxybenzoic acid
| Conditions | Yield |
|---|---|
|
With
methanol;
In
sodium hydroxide;
at 20 ℃;
|
100%
|
|
With
sodium hydroxide;
In
methanol; water;
for 8h;
Reflux;
|
100%
|
|
With
potassium hydroxide;
In
ethanol; water;
for 24h;
Yield given;
Heating;
|
|
|
With
sodium hydroxide;
In
ethanol;
for 1.5h;
Yield given;
Heating;
|
|
|
With
potassium hydroxide;
|
|
|
With
potassium hydroxide;
In
ethanol;
for 14h;
Yield given;
Heating;
|
|
|
With
potassium hydroxide;
In
ethanol;
at 20 ℃;
|
|
|
With
sodium hydroxide;
|
|
|
Multi-step reaction
with
2
steps
1: 76 percent / lithium 2,2,6,6-tetramethylpiperidide / tetrahydrofuran / 1.) 0 deg C, 45 min, 2.) r.t., 1 h
2: 4 percent / manganese(III) acetate, acetic acid / 22 h / Ambient temperature
With
2,2,6,6-tetramethylpiperidinyl-lithium; manganese triacetate; acetic acid;
In
tetrahydrofuran;
|
|
|
With
water; lithium hydroxide;
In
tetrahydrofuran;
|
|
|
With
lithium aluminium tetrahydride;
In
tetrahydrofuran;
at 18 - 25 ℃;
for 1.33333h;
Inert atmosphere;
|
18 g
|
|
With
water; sodium hydroxide;
In
tetrahydrofuran; methanol;
at 20 ℃;
for 70h;
|
3.1 g
|
28917-43-3 Upstream products
-
58605-10-0
methyl 3,5-bis(benzyloxy)benzoate
-
50513-72-9
(3,5-di-benzyloxy)benzoic acid benzyl ester
-
50841-46-8
ethyl 3,5-di(benzyloxy)benzoate
-
99-10-5
3,5-Dihydroxybenzoic acid
28917-43-3 Downstream products
-
144840-93-7
C51 H39 Cl3 O10
-
24131-31-5
3,5-dibenzyloxybenzyl alcohol
-
28917-44-4
3,5-dibenzyloxylbenzoyl chloride
-
111536-61-9
3,5-dibenzyloxy-N-(2-hydroxy-1,1-dimethylethyl)benzamide
