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What is the Benzonatate ?
Benzonatate is pale yellow oily liquid, while it's Molecular Formula is C30H53NO11. Antitussive
What is the CAS number for Benzonatate ?
The CAS number of Benzonatate is 104-31-4.
More information of Benzonatate 104-31-4 are:
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Synonyms |
Benzoicacid, p-(butylamino)-, 2-[2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethylester (8CI);Benzoic acid, p-(butylamino)-, ester with2,5,8,11,14,17,20,23,26-nonaoxaoctacosan-28-ol (6CI,7CI);Benzononantin;Benzononatine;Exangit;KM 65;Tesalon;Tessalin;Tessalon;Tessalon-Ciba;Ventussin;Ventussin-Loz; |
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CAS?Number |
104-31-4 |
|
Molecular Formula |
C30H53NO11 |
|
Molecular Weight |
603.75 |
|
Density |
1.096 g/cm3 |
|
Boiling Point |
649 °C at 760 mmHg |
|
Flash Point |
346.3 °C |
|
PSA |
121.40000 |
|
LogP |
2.90760 |
|
Pka |
2.20±0.39(Predicted) |
What is Benzonatate (104-31-4) used for?
Benzonatate is a reversible voltage-gated sodium channel blocker. It blocks Nav1.7 currents in a concentration- and voltage-dependent manner (IC50s = 5.9 and 1.4 μM at holding potentials of -100 and -70 mV, respectively) and inhibits action potential firing in catecholamine A differentiated (CAD) cells. Benzonatate also blocks 80% of Nav1.3 currents in N1E-115 cells when used at a concentration of 100 μM. In vivo, benzonatate (0.85 mg/min) reduces the frequency, but has no effect on the amplitude, of the cough reflex in anesthetized dogs. Formulations containing benzonatate have been used as antitussive agents for the treatment of coughs.
InChI:InChI=1/C30H53NO11/c1-3-4-9-31-29-7-5-28(6-8-29)30(32)42-27-26-41-25-24-40-23-22-39-21-20-38-19-18-37-17-16-36-15-14-35-13-12-34-11-10-33-2/h5-8,31H,3-4,9-27H2,1-2H3
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How to get the best price on Benzonatate?
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